If only this were the case, the mortality rate of people would be a lot less than it is now. Unfortunately, going to the gym will NOT significantly counteract the adverse effects of being sedentary all day (i.e., working at a job which requires one to sit behind a desk). Increasing the duration and/or intensity of your workout will do little to ameliorate the deleterious effects (e.g., obesity, diabetes, etc.) of sitting all day. Your best bet would be to increase the frequency of your workouts instead (i.e., exercise more days during the week). Blood vessel function cannot be significantly improved with minimal exercise to combat a lifestyle of sedentary behavior. Sitting excessively will lower your HDL (the good cholesterol) as well as raise your triglyceride and blood sugar levels--a recipe for heart disease among other chronic lifestyle-related diseases. If you work at a job that requires prolonged sitting, be sure to get up out of your chair at least once every hour and go for a brief walk. Your blood vessels will thank you!
Brian Danley, CFT
"Motivation is what gets you started. Habit is what keeps you going."
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I'm a personal trainer who loves to help others fulfill their health and fitness goals. I consider myself a bodybuilder in that I live the lifestyle of eating healthy food, working out regularly, and sculpting my body.